Remember how Nagini was a human woman that we learned about?
Nagini was always the snake that was at Voldemort’s side but don’t forget that she was also a woman who completely transformed into a snake and did his bidding.
A snake that was always there for Voldemort, Nagini was the final Horcrux that needed to be defeated (after Harry Potter) in order to take down Voldemort. So why did Fantastic Beasts: The Crimes of Grindelwald decide to make her a woman that just would slowly become a snake?
In a lot of ways, the messaging is confusing because not only was none of this made clear in the original series but then it changes everything about Nagini as a snake. She’s not just his pet that he loves, she’s a willing participant in whatever evil Voldemort chose to do and why? Because he could speak to her?
Sure, yes, Nagini is a Maledictus but the fact that, so far, the reasoning for her connection to Voldemort is probably the Parseltongue seems a bit like she just wanted someone to talk to and wouldn’t stand on her own as just a snake once the curse took hold of her.
It’s a bit confusing because why would a woman willingly stand by Voldemort and do his terrible bidding, especially when she is clearly wronged by Grindelwald before him? It also goes back to Bellatrix being there but Nagini is just a bit upsetting and confusing. Why make her a woman at all when she could have remained his snake but instead they wanted that name to stick out to us and make the storyline even more complicated?